Contraindicated. Coadministration of doravirine with a robust CYP3A inducer may possibly decrease doravirine plasma concentrations and/or effects. Likely for lack of virologic reaction and doable resistance to doravirine.
pentobarbital will decrease the level or outcome of disopyramide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
pentobarbital will minimize the level or influence of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or impact of alprazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the extent or result of isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
pentobarbital will lower the extent or outcome of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. The efficacy of hormonal contraceptives may very well be lowered. Usage of a nonhormonal contraceptive is recommended.
pentobarbital will lessen the extent or result of estropipate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lower the level or impact of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Contraindicated (1)pentobarbital will minimize the extent or result of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or result of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Suggested atogepant dosage with concomitant utilization of powerful or reasonable CYP3A4 inducers is thirty mg or sixty mg qDay.
pentobarbital will lower the extent or influence of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Keep track of Closely (3)pentobarbital will decrease the extent or influence of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Strong or reasonable CYP3A4 inducers may possibly enhance fee of diazepam elimination; for that reason, efficacy of diazepam could possibly be reduced.
Likely for Fake optimistic test results if macimorelin and robust CYP3A4 inducers are coadministered. Discontinue sturdy CYP3A4 inducer, making it possible for for sufficient washout time, in advance of testing.
pentobarbital will minimize the extent or influence get more info of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.